Complex DNA assembly

Dynamic DNA device

Application


Song, J.; Li, Z.; Wang, P.; Meyer, T.; Mao, C.; Ke, Y.; Reconfiguration of DNA Molecular Arrays Driven by Information Relay. Science 2017, doi: 10.1126/science.aan3377.

Wang, P.; Gaitanaros, S.; Lee, S.; Bathe, M.; Shih, W. M.; Ke, Y.; Programming Self-Assembly of DNA Origami Honeycomb Two-Dimensional Lattices and Plasmonic Metamaterials. Journal of the American Chemical Society 2016, 138(24), 7733.

Shen, C.; Lan, X.; Lu, X.; Meyer, T. A.; Ni, W.; Ke, Y.; Wang, Q.; Site-Specific Surface Functionalization of Gold Nanorods Using DNA Origami Clamps. Journal of the American Chemical Society 2016, 138(6), 1764-1767.

Iinuma, R.; Ke, Y.; Jungmann, R.; Schlichthaerle, T.; Woehrstein, J.; Yin, P. Polyhedra Self-Assembled from DNA Tripods and Characterized with 3D DNA-PAINT. Science 2014, 344, 65–69.

Nickels, P.; Ke, Y.; Jungmann, R.; Smith, D.; Leichsenring, M.; Shih, W.; and Liedl, T.; Hogberg, B. DNA Origami Structures Directly Assembled from Intact Bacteriophages. Small 2014, 10, 1765-1769.

Ke, Y.; Bellot, G.; Voigt, N.; Fradkov, E. Two Design Strategies for Enhancement of Multilayer–DNA-Origami Folding: Underwinding for Specific Intercalator Rescue and Staple-Break Positioning. Chemical Science 2012, 3, 2587–2597.

Ke, Y.; Voigt, N. V.; Gothelf, K. V.; Shih, W. M. Multilayer DNA Origami Packed on Hexagonal and Hybrid Lattices. Journal of the American Chemical Society 2012, 134, 1770–1774.


Ong, L.L.; Hanikel, N.; Yaghi, O.K.; Grun, C.; Strauss, M.T.; Bron, P.; Lai-Kee-Him, J.; Schueder, F.; Wang, B.; Wang, P.; Kishi, J.Y.; Myhrvold, C.A.; Zhu, A.; Jungmann, R.; Bellot, G.; Ke, Y.; Yin, P.; Programmable self-assembly of three-dimensional nanostructures from 10^4 unique components. Nature in press.

Ke, Y.; Ong, L. L.; Sun, W.; Song, J.; Dong, M.; Shih, W. M.; Yin, P. DNA Brick Crystals with Prescribed Depth. Nature Chemistry 2014, 6, 994-1002.

Wei, B.; Dai, M.; Myhrvold, C.; Ke, Y.; Jungmann, R.; Yin, P. Design Space for Complex DNA Structures. Journal of the American Chemical Society 2013, 135, 18080-18088.

Ke, Y.; Ong, L. L.; Shih, W. M.; Yin, P. Three-Dimensional Structures Self-Assembled from DNA Bricks. Science 2012, 338, 1177-1183.


Song, J.; Li, Z.; Wang, P.; Meyer, T.; Mao, C.; Ke, Y.; Reconfiguration of DNA Molecular Arrays Driven by Information Relay. Science 2017, doi: 10.1126/science.aan3377.

Zhan, P.; Dutta, P.K.; Wang, P.; Song G.; Dai, M.; Zhao, S.; Wang, Z.; Yin, P.; Zhang, W.; Ding, B.; Ke, Y.; Reconfigurable Three-Dimensional Gold Nanorod Plasmonic Nanostructures Organized on DNA Origami Tripod. ACS Nano 2017, 11(2), 1172-1179.

Ke, Y.; Meyer, T.; Shih, W.M.; Bellot, G.; Regulation at a distance of biomolecular interactions using a DNA origami nanoactuator. Nature Communications 2016, 18(7),10935.


Lan, X.; Su, Z.; Zhou, Y.; Meyer, T.; Ke, Y.; Wang, Q.; Chiu, W.; Liu, N.; Zou, S.; Yan, H.; Liu, Y.; Programmable Supra-Assembly of DNA Surface Adapter for Tunable Chiral Directional Self-Assembly of Gold Nanorods. Angewandte Chemie 2017, 491, 51.

Jiang, T.; Meyer, T.; Modlin, C.; Zou, X.; Conticello, V.P.; Ke, Y.; Structurally Ordered Nanowire Formation from Co-Assembly of DNA Origami and Collagen-Mimetic Peptides. Journal of the American Chemical Society 2017, 139(40), 14025.

Zhan, P.; Dutta, P.K.; Wang, P.; Song G.; Dai, M.; Zhao, S.; Wang, Z.; Yin, P.; Zhang, W.; Ding, B.; Ke, Y.; Reconfigurable Three-Dimensional Gold Nanorod Plasmonic Nanostructures Organized on DNA Origami Tripod. ACS Nano 2017, 11(2), 1172-1179.

Wang, P.; Gaitanaros, S.; Lee, S.; Bathe, M.; Shih, W. M.; Ke, Y.; Programming Self-Assembly of DNA Origami Honeycomb Two-Dimensional Lattices and Plasmonic Metamaterials. Journal of the American Chemical Society 2016, 138(24), 7733.

Urban, M.J.; Dutta, P.K.; Wang, P.; Duan, X.; Shen, X.; Ding, B.; Ke, Y.; Liu, N.; Plasmonic Toroidal Metamolecules Assembled by DNA Origami. Journal of the American Chemical Society 2016, 138(17), 5495.

Jiang, H.; Pan, V.; Vivek, S.; Weeks, E. R.; Ke, Y.; Programmable DNA Hydrogels Assembled from Multi-Domain DNA Strands. ChemBioChem 2016, 17, 1156–1162.

Shen, C.; Lan, X.; Lu, X.; Meyer, T. A.; Ni, W.; Ke, Y.; Wang, Q.; Site-Specific Surface Functionalization of Gold Nanorods Using DNA Origami Clamps. Journal of the American Chemical Society 2016, 138(6), 1764-1767.

Tian, Y.; Wang, T.; Liu, W.; Xin, H.; Li, H.; Ke, Y.; Shih, W.; Gang, O. Prescribed nanoparticle cluster architectures and low-dimensional arrays built using octahedral DNA origami frames. Nature Nanotechnology 2015, 10(7), 637-644.

Lan, X.; Lu, X.; Shen, C.; Ke, Y.; Ni, W.; & Wang, Q. Au Nanorod Helical Superstructures with Designed Chirality. Journal of the American Chemical Society 2015, 137(1), 457–462.

Jin, Z.; Sun, W.; Ke, Y.; Shih, C.; Paulus, G. L. C.; Wang, Q. H.; Mu, B.; Yin, P.; Strano, M. S. Metalized DNA Nanolithography for Encoding and Transferring Spatial Information for Graphene Patterning. Nature Communications 2013, 4, 1663-1671.


Wang, P.; Rahman, M.A.; Zhao, Z.; Weiss, K.; Zhang, C.; Chen, Z.; Hurwitz, S.J.; Chen, Z.G.; Shin, D.M.; Ke, Y.; Systemic Delivery of Bcl2-Targeting siRNA by DNA Nanoparticles Suppresses Cancer Cell Growth. Visualization of the Cellular Uptake and Trafficking of DNA Origami Nanostructures in Cancer Cells. Journal of the American Chemical Society 2018, 140(7), 2478-2484.

Rahman, M.A.; Wang, P.; Zhao, Z.; Wang, D.; Nannapaneni, S.; Zhang, C.; Chen, Z.; Griffith, C.C.; Hurwitz, S.J.; Chen, Z.G.; Ke, Y.; Shin, D.M.; Systemic Delivery of siRNA by DNA Nanoparticles Targeting Bcl2 in Cancer Cell Growth. Angewandte Chemie 2017.